Enzyme-linked immunosorbent assay (ELISA) to detect antibodies in gonorrhea using whole cells.

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Enzyme-linked immunosorbent assay (ELISA) to detect antibodies in gonorrhea using whole cells.

The choice of an antigen that will adequately differentiate between infected and non-infected patients has been a problem in detecting gonococcal antibodies for diagnosis. We have used the sensitive technique of ELISA to test various serotypes of Neisseria gonorrhoeae for their suitability as antigens. Whole cells of each serotype were attached to polystyrene plates using poly-L-lysine, N gonor...

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The ELISA, enzyme-linked immunosorbent assay.

Featured Article: Engvall E, Perlmann P. Enzymelinked immunosorbent assay (ELISA). Quantitative assay of immunoglobulin G. Immunochemistry 1971;8:871– 4. This paper was my first as a graduate student of Professor Peter Perlmann at Stockholm University. At the time, RIAs were in full bloom, but they were too sophisticated for many areas of research and diagnosis because they required expensive e...

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ژورنال

عنوان ژورنال: Journal of Clinical Pathology

سال: 1981

ISSN: 0021-9746

DOI: 10.1136/jcp.34.9.1040